Pre Flight Thrombophilia Screen (DVT)
Haematology Overview / Directory
Purpose of the test
It is now recognised that long-haul air travel increases the risk of DVT, particularly in passengers who have other risk factors for thrombosis (eg pregnancy, recent surgery, hormone treatments, thrombophilia, previous DVT).
For most passengers, common sense measures including in–flight exercise and avoidance of dehydration are sufficient to prevent DVT. In travellers with thrombophilia, the use of compression stockings and/or anticoagulant medications should be considered.
The screen includes Factor V Leiden, Prothrombin Gene Mutation 20210 G/A and Anticardiolipin Antibodies.
Reference Range
Normal Factor V Leiden screen: G/G
Normal Prothrombin Gene Mutation 20210A screen:G/G
Anticardiolipin Antibodies - Negative
Sample Requirements
4.5 mls of EDTA anticoagulated blood (lavender top) and 5mls of non-anticoagulated blood (gold top)
Storage and Transport
Samples should be kept at between 2-4 degrees Celsius and transported to the laboratory within 4 hours
Turnaround Time
2 weeks
Contacts
Haemostasis Laboratory on 020 3299 9000 ext 2434
or
email liz.ford@nhs.net
