Purpose of the test
The Red Cell Protein Laboratory provides a comprehensive service for the detection of haemoglobin variants and thalassaemias.
Initial analysis is by HPLC which will screen for any haemoglobin variants and give an HbA2 level for beta thalassaemia identification.
Further tests will be performed depending on HPLC results, red cell indices and clinical details. This could include solubility test, citrate and acid electrophoresis or HbH bodies. For uncommon haemoglobin variants further analysis by iso-electric focussing can be undertaken.
All samples sent for analysis will get an interpretive comment relevant to the clinical details.
Molecular analysis can be undertaken by the Prenatal diagnosis section.
Minimum 1 ml EDTA blood.
It is recommended a FBC is performed and results sent with sample for interpretive purposes. For full interpretive comments ethnic origin information is required.
Storage and Transport
Samples can be sent first class post. Samples can tested up to 14 days after collection.
Results available on Results Online within 5 working days
Time Limit for Extra Tests
Depends on tests required. Contact laboratory for further details.
Factors affecting results or interpretation
Recent blood transfusion.
Tel 020 3299 9000 Laboratory Ext 2455 Office Ext 4337