Anti Cardiolipin antibodies
Immunology and Allergy Overview / Directory
Purpose of the test
Anti-phospholipid syndrome (APS), also known as Hughes syndrome, presents with diverse clinical symptoms, the more overt being thrombosis and recurrent miscarriage. APS is characterised by the presence of autoantibodies to a variety of phospholipid molecules, among which, is cardiolipin. The detection of anti-cardiolipin antibodies is a major part of the laboratory investigation of APS and of systemic lupus erythematosus (SLE) where up to 50% of patients also have these autoantibodies. Both IgG and IgM autoantibodies are of clinical relevance and to that end we offer an anti-cardiolipin assay for both isotypes.
Sample Requirements
2 ml freshly separated serum
Storage and Transport
Serum stored at 4°C should be sent by first class post
Turnaround Time
6 working days
Time Limit for Extra Tests
Five days
Factors affecting results or interpretation
All tests are compromised by prolonged transit times. For this reason, date of bleed and date of postage must be provided with each request.
Price
Price available on application - please contact adrianturner1@nhs.net. Discounts could be available for significant workloads.
Contacts
John Cazabon or Rosemary Ebling, Lead Biomedical Scientists
T 020 3299 1559
Dr Ted Davies Consultant Clinical Scientist
T 020 3299 9000 Ex 8752
