Anti Thyroid Peroxidase antibodies
Immunology and Allergy Overview / Directory
Purpose of the test
This ELISA based assay uses a highly purified human thyroid peroxidase (TPO) as antigen. The literature suggests that between 75% and 90% of patients with Hashimoto’s thyroiditis have anti-TPO antibodies. The autoantibody is also present in 75% of patients with Graves’ disease and some 60% with postpartum thyroiditis. Anti-TPO may also be found in sub-clinical hypothyroidism (normal free T4 and elevated TSH) and as part of the spectrum of autoimmune endocrinopathies.
Sample Requirements
2 ml freshly separated serum
Storage and Transport
Serum stored at 4°C should be sent by first class post
Turnaround Time
5 working days
Time Limit for Extra Tests
Five days
Factors affecting results or interpretation
All tests are compromised by prolonged transit times. For this reason, date of bleed and date of postage must be provided with each request.
Price
Price available on application - please contact adrianturner1@nhs.net. Discounts could be available for significant workloads.
Contacts
John Cazabon or Rosemary Ebling, Lead Biomedical Scientists
T 020 3299 1559
Dr Ted Davies Consultant Clinical Scientist
T 020 3299 9000 Ex 8752
