Anti Haemophilus Influenzae (IgG) antibodies
Immunology and Allergy Overview / Directory
Purpose of the test
This antibody is one of a group of antibodies commonly referred to as “functional antibodies”. The others in this designation are anti-pneumococcal, anti-Tetanus toxin and anti-Diphtheria toxin antibodies.
Functional antibodies are a more sensitive tool than either total serum IgG or IgG subclasses in detecting patients who fail to respond to natural infection or antigenic challenge. In cases where immunisation is performed we recommend that both pre and post immunisation samples are assessed in the same assay.
This test measures IgG antibodies to H. influenzae type b capsular antigens. The basal protective level is reported as 0.15 µg/ml and the optimal level at 1.0 µg/ml.
Sample Requirements
2 ml freshly separated serum
Storage and Transport
Serum stored at 4°C should be sent by first class post
Turnaround Time
15 working days
Time Limit for Extra Tests
Five days
Factors affecting results or interpretation
All tests are compromised by prolonged transit times. For this reason, date of bleed and date of postage must be provided with each request.
Immunisation history with dates must be given with all requests for "Specific Antibodies"
Price
Price available on application - please contact adrianturner1@nhs.net. Discounts could be available for significant workloads.
Contacts
Dr Ted Davies, Consultant Clinical Scientist
T 020 3299 9000 Ex 8752
John Cazabon or Rosemary Ebling, Lead Biomedical Scientists
T 020 3299 1559
