Immunology and Allergy Overview / Directory
Purpose of the test
This investigation measures the concentration of C1 esterase inhibitor. It is used in the diagnosis of hereditary angioedema or acquired angioedema. 15% of patients with hereditary angioedema will have normal concentrations of C1 esterase inhibitor, due to a non-functioning protein.
Sample Requirements
0.5 ml freshly separated serum.
Storage and Transport
Serum stored at 4°C should be sent by 1st class post as soon as possible.
Turnaround Time
28 days
Time Limit for Extra Tests
Five days
Factors affecting results or interpretation
All tests are compromised by prolonged transit times. For this reason, date of bleed and date of postage must be provided with each request.
Price
Price available on application - please contact adrianturner1@nhs.net. Discounts could be available for significant workloads.
Contacts
John Cazabon or Rosemary Ebling, Lead Biomedical Scientists
T 020 3299 1559
E john.cazabon@nhs.net
E rosemary.ebling@nhs.net
Allergen Specific IgE (Phadia Immunocap)
Anti Adrenal antibodies
Anti Cardiolipin antibodies
Anti Centromere antibodies
Anti dsDNA antibodies
Anti ENA antibodies
Anti Endomysial Antibodies
Anti Glomerular Basement Membrane Antibodies
Anti Glutamic Acid Decarboxylase (GAD) Antibodies
Anti Haemophilus Influenzae (IgG) antibodies
Anti Intrinsic factor Antibodies
Anti Liver Cytosol 1 blot
Anti LKM1 blot
Anti Mitochondrial M2 blot
Anti MPO & PR3
Anti Neutrophil Cytoplasmic Antibodies (ANCA)
Anti Nuclear Antibodies
Anti Ovarian antibodies
Anti Pneumococcal Capsular Polysaccharide antibodies (IgG, I
Anti Skin antibodies
Anti Soluble Liver Antigen blot
Anti Striated Muscle antibodies
Anti Tetanus Toxoid Antibodies (IgG)
Anti Thyroid Peroxidase antibodies
Anti Tissue Transglutaminase antibodies
Anti-cyclic citrullinated peptide antibody (Anti-CCP)
Antigenic C1 inhibitor concentration
Autoantibodies (ASM, LKM, MITO, GPC)
Autoimmune Liver Blot Screen (LC1, LKM, M2, SLA)
Beta 2 microglobulin concentration
Complement (C3 & C4)
Diabetes Autoantibodies (INS, GAD, IA2)
Immunoglobulin E concentration (IgE)
Immunoglobulin G Subclasses (1-4)
Immunoglobulins Concentrations (IgG, IgA, IgM)
Lymphocyte Subset Enumeration
Paraproteins (serum protein electrophoresis)
Rheumatoid Factor
Serum Free Light Chains (SFLC)
Serum Paraprotein Immunotyping
Serum tryptase
T Cell Subsets
