Liver Pathology
Liver Pathology
Liver Pathology is part of the Institute of Liver Studies at King's College Hospital NHS Foundation Trust. The Institute of Liver Studies encompasses the clinical service and academic activities (undergraduate and postgraduate teaching and overlapping research) in adult and paediatric hepatology, hepatobiliary surgery and liver transplantation at King's. It was established in 1966 and is the largest specialist centre for the treatment of Liver disease in Europe.
The department admits patients from the UK and abroad, holding approximately 10,000 outpatient appointments and performing 200 liver transplants a year.
The Institute of Liver Studies consists of the Todd ward, part of the Dawson ward and part of the RD Lawrence ward, the Liver Transplant Theatre, the Liver Intensive Therapy Unit, the Liver Outpatients' Department, Liver Endoscopy, Paediatric hepatology and the Laboratories (Liver Pathology and academic laboratories).
Liver Pathology provides a specialist diagnostic and drug monitoring service for the clinical management of liver patients. Although Liver Pathology primarily supports Adult and Paediatric Liver services and some other departments at King's, it also provides specialist services to referring clinicians at centres outside King's (from United Kingdom and abroad).
Liver Pathology is fully CPA accredited (CPA ref no. 2321)
We provide 3 services within Liver Pathology:
A) Clinical Biochemistry - Immunosuppressive Drug Monitoring Service (idm)
The IDM service supports prescribed immunosuppressive therapy of adult and paediatric liver patients and sensitive analysis of Tacrolimus, Ciclosporin, Mycophenolic acid, Sirolimus and Everolimus using liquid chromatography-tandem mass-spectrometry. Interpretative advice to aid optimal clinical management of patients is also provided.
Contacts:
Section-Head (IDM):
Dr J. Michael Tredger, Consultant Clinical Scientist
T 020 3299 3147
Lead-Clinician:
Professor Nigel Heaton, Consultant Surgeon and Professor of Transplant Surgery
B) Virology - Hepatitis Testing Service (hts)
The virology hepatitis testing service provides diagnostic tests for Hepatitis A, B, C, D, and E to support the Hepatitis clinics, Liver transplantation and Liver intensive care, as well as GPs and other hospitals.
The tests provided by the Virology hepatitis testing service include: HAV Ab (Total), HAV Ab (IgM), HBsAg, HBsAg Confirmatory, HBsAb, HBeAg, HBeAb, HBcAb (Total), HBcAb (IgM), HBVDNA Quantitative, HBV Drug Resistance testing, HBV Genotype, HCV Ab, HCV RNA Quantitative, HCV Genotype, Delta Ab (Total), Delta Ab (IgM), HDV RNA, HEV Ab (IgM), HEV Ab (IgG), HEV RNA
Contacts:
Section Manager of Hepatitis Testing:
Dr Dazhuang Shang
T 020 3299 3732
Lead-Clinician:
Dr Kosh Agarwal, Consultant Hepatologist
C) Histopathology Service (his)
The Histopathology Service provides full diagnostic support to clinicians and surgeons caring for adult and paediatric patients with liver, biliary tree or pancreatic disorders. It is renowned nationally and internationally as a referral centre.
The department comprises three Consultant Histopathologists and a team of Biomedical Scientists who handle liver biopsies, whole or part of organs resection specimens, and referrals for expert opinion from other centres. There is also an active postgraduate pathology teaching programme.
The Histopathology service offers a rapid expert diagnostic service for small biopsies, a 24/7 service for frozen section diagnosis and commitment to research and development of new diagnostic techniques.
Contacts:
Section-head and clinical lead of Histopathology:
Dr Alberto Quaglia, Consultant Histopathologist
T 020 3299 1810
